Orthopedic Surgery
Management and Optimization of Hemostasis
Antifibrinolytic Agents
Intraoperative pharmacotherapeutic blood management strategies in total knee arthroplasty. (opens new window)
Source: J Knee Surg 2013;26(6):379-85.
Indexed: PubMed 23955184
DOI: 10.1055/s-0033-1353992
https://www.ncbi.nlm.nih.gov/pubmed/23955184 (opens new window)
Tranexamic acid in patients undergoing noncardiac surgery. (opens new window)
Source: N Engl J Med. 2022;386(21):1986-97.
Indexed: PubMed 35363452
DOI: 10.1056/NEJMoa2201171
https://pubmed.ncbi.nlm.nih.gov/35363452/ (opens new window)
Repeat-dose intravenous tranexamic acid further decreases blood loss in total knee arthroplasty. (opens new window)
Source: Int Orthop 2013;37(3):441-5.
Indexed: PubMed 23371424
DOI: 10.1007/s00264-013-1787-7
https://www.ncbi.nlm.nih.gov/pubmed/23371424 (opens new window)
The efficacy of combined use of intraarticular and intravenous tranexamic acid on reducing blood loss and transfusion rate in total knee arthroplasty. (opens new window)
Source: J Arthroplasty 2015;30(5):776-80.
Indexed: PubMed 25534864
DOI: 10.1016/j.arth.2014.12.001
https://www.ncbi.nlm.nih.gov/pubmed/25534864 (opens new window)
Efficacy and Safety of Antifibrinolytic Agents in Reducing Perioperative Blood Loss and Transfusion Requirements in Scoliosis Surgery: A Systematic Review and Meta-Analysis. (opens new window)
Source: PLoS One 2015;10(9):e0137886.
Indexed: PubMed 26382761
DOI: 10.1371/journal.pone.0137886
https://www.ncbi.nlm.nih.gov/pubmed/26382761 (opens new window)
Oral is as effective as intravenous tranexamic acid at reducing blood loss in thoracolumbar spinal fusions: a prospective randomized trial. (opens new window)
Source: Spine 2022;47(2):91-8.
Indexed: PubMed 34224510
DOI: 10.1097/BRS.0000000000004157
https://pubmed.ncbi.nlm.nih.gov/34224510/ (opens new window)
Recombinant Activated Factor VII (rFVIIa)
The use of recombinant factor VIIa for severe intractable bleeding during spine surgery. (opens new window)
Source: Spine 2004;29(12):1384-7.
Indexed: PubMed 15187645
https://www.ncbi.nlm.nih.gov/pubmed/15187645 (opens new window)
Topical Hemostatic Agents
A comprehensive review of topical hemostatic agents: efficacy and recommendations for use. (opens new window)
Source: Ann Surg 2010;251(2):217-28.
Indexed: PubMed 20010084
DOI: 10.1097/SLA.0b013e3181c3bcca
https://www.ncbi.nlm.nih.gov/pubmed/20010084 (opens new window)
Hemostatic techniques reduce hospital stay following multilevel posterior cervical spine surgery. (opens new window)
Source: J Bone Joint Surg Am 2012;94(21):1952-8.
Indexed: PubMed 23138237
DOI: 10.2106/JBJS.K.00632
https://www.ncbi.nlm.nih.gov/pubmed/23138237 (opens new window)
The efficacy of bone wax in reduction of perioperative blood loss in total hip arthroplasty via direct anterior approach: a prospective randomized clinical trial. (opens new window)
Source: J Bone Joint Surg Am. 2022;104(20):1805-13.
Indexed: PubMed 35984033
DOI: 10.2106/JBJS.22.00376
https://pubmed.ncbi.nlm.nih.gov/35984033/ (opens new window)
Use of a fibrin sealant within a blood-saving protocol in patients undergoing revision hip arthroplasty: effects on post-operative blood transfusion and healthcare-related cost analysis. (opens new window)
Source: Int Orthop 2019;43(12):2707-14.
Indexed: PubMed 30671601
DOI: 10.1007/s00264-019-04291-4
https://www.ncbi.nlm.nih.gov/pubmed/30671601 (opens new window)